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5 Facts you should know about

Ménétrier disease

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1

The stomach is characterized by large, tortuous gastric folds in the fundus and body, with the antrum generally spared, giving the mucosa a cobblestone or cerebriform appearance

2

The disorder is associated with excessive secretion of transforming growth factor alpha (TGF-α)

3

This leads to excessive mucus production, causing protein loss from the stomach and low or absent levels of stomach acid

4

Symptoms may include pain in the upper middle region of the stomach, nausea, vomiting, and diarrhea

 

5

The cause of Ménétrier disease is unknown, but it has been associated with human cytomegalovirus (HCMV) infection in children and H. pylori infections in adults

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